Folyóiratcikkek tallózása szerző szerint "Hunyady, László"

A találatok rendezése: Rendezés: Találatok:

  • A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase 
    Tóth, András Dávid; Garger, Dániel; Prokop, Susanne; Soltész-Katona, Eszter; Várnai, Péter; Balla, András; Turu, Gábor; Hunyady, László (2021)
  • Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization 
    Tóth, András; Gyombolai, Pál; Szalai, Bence; Várnai, Péter; Turu, Gábor; Hunyady, László (2017)
    Heterodimerization between angiotensin type 1A receptor (AT1R) and β2-adrenergic receptor (β2AR) has been shown to modulate G protein-mediated effects of these receptors. Activation of G protein-coupled receptors (GPCRs) ...
  • BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation 
    Tóth, József T; Gulyás, Gergő; Tóth, Dániel J; Balla, András; Hammond, Gerald RV; Hunyady, László; Balla, Tamás; Várnai, Péter (2016)
    Deciphering many roles played by inositol lipids in signal transduction and membrane function demands experimental approaches that can detect their dynamic accumulation with subcellular accuracy and exquisite sensitivity. ...
  • Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen 
    Menden, MP; Wang, D; Mason, MJ; Szalai, Bence; Bulusu, KC; Guan, Y; Yu, T; Kang, J; Jeon, M; Wolfinger, R; Nguyen, T; Zaslavskiy, M; Abante, J; Abecassis, BS; Aben, N; Aghamirzaie, D; Aittokallio, T; Akhtari, FS; Al-lazikani, B; Alam, T; Allam, A; Allen, C; de Almeida, MP; Altarawy, D; Alves, V; Amadoz, A; Anchang, B; Antolin, AA; Ash, JR; Aznar, VR; Ba-alawi, W; Bagheri, M; Bajic, V; Ball, G; Ballester, PJ; Baptista, D; Bare, C; Bateson, M; Bender, A; Bertrand, D; Wijayawardena, B; Boroevich, KA; Bosdriesz, E; Bougouffa, S; Bounova, G; Brouwer, T; Bryant, B; Calaza, M; Calderone, A; Calza, S; Capuzzi, S; Carbonell-Caballero, J; Carlin, D; Carter, H; Castagnoli, L; Celebi, R; Cesareni, G; Chang, H; Chen, G; Chen, H; Chen, H; Cheng, L; Chernomoretz, A; Chicco, D; Cho, K-H; Cho, S; Choi, D; Choi, J; Choi, K; Choi, M; Cock, MD; Coker, E; Cortes-Ciriano, I; Cserzö, Miklós; Cubuk, C; Curtis, C; Daele, DV; Dang, CC; Dijkstra, T; Dopazo, J; Draghici, S; Drosou, A; Dumontier, M; Ehrhart, F; Eid, F-E; ElHefnawi, M; Elmarakeby, H; van Engelen, B; Engin, HB; de Esch, I; Evelo, C; Falcao, AO; Farag, S; Fernandez-Lozano, C; Fisch, K; Flobak, A; Fornari, C; Foroushani, ABK; Fotso, DC; Fourches, D; Friend, S; Frigessi, A; Gao, F; Gao, X; Gerold, JM; Gestraud, P; Ghosh, S; Gillberg, J; Godoy-Lorite, A; Godynyuk, L; Godzik, A; Goldenberg, A; Gomez-Cabrero, D; Gonen, M; de Graaf, C; Gray, H; Grechkin, M; Guimera, R; Guney, E; Haibe-Kains, B; Han, Y; Hase, T; He, D; He, L; Heath, LS; Hellton, KH; Helmer-Citterich, M; Hidalgo, MR; Hidru, D; Hill, SM; Hochreiter, S; Hong, S; Hovig, E; Hsueh, Y-C; Hu, Z; Huang, JK; Huang, RS; Hunyady, László; Hwang, J; Hwang, TH; Hwang, W; Hwang, Y; Isayev, O; Don’t Walk, OB IV; Jack, J; Jahandideh, S; Ji, J; Jo, Y; Kamola, PJ; Kanev, GK; Karacosta, L; Karimi, M; Kaski, S; Kazanov, M; Khamis, AM; Khan, SA; Kiani, NA; Kim, A; Kim, J; Kim, J; Kim, K; Kim, K; Kim, S; Kim, Y; Kim, Y; Kirk, PDW; Kitano, H; Klambauer, G; Knowles, D; Ko, M; Kohn-Luque, A; Kooistra, AJ; Kuenemann, MA; Kuiper, M; Kurz, C; Kwon, M; van Laarhoven, T; Laegreid, A; Lederer, S; Lee, H; Lee, J; Lee, YW; Lepp_aho, E; Lewis, R; Li, J; Li, L; Liley, J; Lim, WK; Lin, C; Liu, Y; Lopez, Y; Low, J; Lysenko, A; Machado, D; Madhukar, N; Maeyer, DD; Malpartida, AB; Mamitsuka, H; Marabita, F; Marchal, K; Marttinen, P; Mason, D; Mazaheri, A; Mehmood, A; Mehreen, A; Michaut, M; Miller, RA; Mitsopoulos, C; Modos, D; Moerbeke, MV; Moo, K; Motsinger-Reif, A; Movva, R; Muraru, S; Muratov, E; Mushthofa, M; Nagarajan, N; Nakken, S; Nath, A; Neuvial, P; Newton, R; Ning, Z; Niz, CD; Oliva, B; Olsen, C; Palmeri, A; Panesar, B; Papadopoulos, S; Park, J; Park, S; Park, S; Pawitan, Y; Peluso, D; Pendyala, S; Peng, J; Perfetto, L; Pirro, S; Plevritis, S; Politi, R; Poon, H; Porta, E; Prellner, I; Preuer, K; Pujana, MA; Ramnarine, R; Reid, JE; Reyal, F; Richardson, S; Ricketts, C; Rieswijk, L; Rocha, M; Rodriguez-Gonzalvez, C; Roell, K; Rotroff, D; de Ruiter, JR; Rukawa, P; Sadacca, B; Safikhani, Z; Safitri, F; Sales-Pardo, M; Sauer, S; Schlichting, M; Seoane, JA; Serra, J; Shang, M-M; Sharma, A; Sharma, H; Shen, Y; Shiga, M; Shin, M; Shkedy, Z; Shopsowitz, K; Sinai, S; Skola, D; Smirnov, P; Soerensen, IF; Soerensen, P; Song, J-H; Song, SO; Soufan, O; Spitzmueller, A; Steipe, B; Suphavilai, C; Tamayo, SP; Tamborero, D; Tang, J; Tanoli, Z-U-R; Tarres-Deulofeu, M; Tegner, J; Thommesen, L; Tonekaboni, SAM; Tran, H; Troyer, ED; Truong, A; Tsunoda, T; Turu, Gábor; Tzeng, G-Y; Verbeke, L; Videla, S; Vis, D; Voronkov, A; Votis, K; Wang, A; Wang, H-QH; Wang, P-W; Wang, S; Wang, W; Wang, X; Wang, X; Wennerberg, K; Wernisch, L; Wessels, L; van Westen, GJP; Westerman, BA; White, SR; Willighagen, E; Wurdinger, T; Xie, L; Xie, S; Xu, H; Yadav, B; Yau, C; Yeerna, H; Yin, JW; Yu, M; Yu, MH; Yun, SJ; Zakharov, A; Zamichos, A; Zanin, M; Zeng, L; Zenil, H; Zhang, F; Zhang, P; Zhang, W; Zhao, H; Zhao, L; Zheng, W; Zoufir, A; Zucknick, M; AstraZeneca-Sanger, Drug Combination DREAM Consortium; Jang, IS; Ghazoui, Z; Ahsen, ME; Vogel, R; Neto, EC; Norman, T; Tang, EKY; Garnett, MJ; Veroli, GYD; Fawell, S; Stolovitzky, G; Guinney, J; Dry, JR; Saez-Rodriguez, J (2019)
    The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven ...
  • Control of myogenic tone and agonist induced contraction of intramural coronary resistance arterioles by cannabinoid type 1 receptors and endocannabinoids. 
    Szekeres, Mária; Nádasy, György László; Soltész-Katona, Eszter; Hunyady, László (2018)
    It was tested whether intrinsic CB1R activation modifies myogenic and agonist induced contraction of intramural coronary resistance arteries of the rat. CB1R protein was detected by immuno-histochemistry and by Western ...
  • Differential beta-arrestin2 requirements for constitutive and agonist-induced internalization of the CB cannabinoid receptor 
    Gyombolai, Pál; Boros, Eszter; Hunyady, László; Turu, Gábor (2013)
    CB1 cannabinoid receptor (CB1R) undergoes both constitutive and agonist-induced internalization, but the underlying mechanisms of these processes and the role of beta-arrestins in the regulation of CB1R function are not ...
  • Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors. 
    Prokop, Susanne Clara; Perry NA; Vishnivetskiy SA; Tóth, András; Inoue A; Milligan G; Iverson TM; Hunyady, László; Gurevich VV (2017)
    Non-visual arrestins interact with hundreds of different G protein-coupled receptors (GPCRs). Here we show that by introducing mutations into elements that directly bind receptors, the specificity of arrestin-3 can be ...
  • Editorial: Molecular Endocrinology Special Feature Minireviews for August 2013: GPCRs in Endocrine Physiology and Pathophysiology 
    Hunyady, László; DeFranco, Donald B (2013)
  • Endocannabinoid-mediated modulation of G protein-coupled receptor signaling-induced vasoconstriction and hypertension. 
    Szekeres, Mária; Nádasy, György László; Turu, Gábor; Soltész-Katona, Eszter; Benyó, Zoltán; Offermanns S; Ruisanchez, Éva; Szabó, Eszter; Takats Z; Batkai S; Tóth, Zsuzsanna; Hunyady, László (2015)
    Activation of G protein-coupled receptors (GPCRs) can induce vasoconstriction via calcium signal-mediated and Rho-dependent pathways. Earlier reports have shown that diacylglycerol produced during calcium signal generation ...
  • Heterologous phosphorylation–induced formation of a stability lock permits regulation of inactive receptors by beta-arrestins 
    Tóth, András; Prokop, Susanne Clare; Gyombolai, Pál; Várnai, Péter; Balla, András; Gurevich, Vsevolod V; Hunyady, László; Turu, Gábor (2018)
    -Arrestins are key regulators and signal transducers of G protein– coupled receptors (GPCRs). The interaction between receptors and -arrestins is generally believed to require both receptor activity and phosphorylation by ...
  • Hypothyroidism-associated missense mutation impairs NADPH oxidase activity and intracellular trafficking of Duox2 
    Donkó, Ágnes; Moranda S; Korzeniowska A; Boudreaua HE; Zana, Melinda; Hunyady, László; Geiszt, Miklós; Leto TL (2014)
  • Investigation of the fate of type I angiotensin receptor after biased activation 
    Szakadáti, Gyöngyi; Tóth, András; Olah I,; Erdélyi, László Sándor; Balla T,; Várnai, Péter; Hunyady, László; Balla, András (2015)
    Biased agonism on the type I angiotensin receptor (AT1-R) can achieve different outcomes via activation of G protein-dependent and -independent cellular responses. In this study, we investigated whether the biased activation ...
  • Minireview: MIRomics in Endocrinology: A Novel Approach for Modeling Endocrine Diseases. 
    Szabó PM; Butz, Henriett; Igaz, Péter; Rácz, Károly; Hunyady, László; Patócs, Attila Balázs (2013)
  • Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis 
    Erdélyi, László Sándor; Mann, Alexander W; Morris-Rosendahl, Deborah J; Groß, Ute; Nagel, Mato; Várnai, Péter; Balla, András; Hunyady, László (2015)
    Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a recently discovered rare disease caused by gain-of-function mutations of the V2 vasopressin receptor gene, AVPR2. To date, mutations of Phe229 and Arg137 have ...
  • Novel mechanisms of G-protein-coupled receptors functions: AT1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk 
    Tóth, András; Turu, Gábor; Hunyady, László; Balla, András (2018)
    AT1 angiotensin receptor (AT1R), a prototypical G protein-coupled receptor (GPCR), is the main receptor, which mediates the effects of the renin-angiotensin system (RAS). AT1R plays a crucial role in the regulation of blood ...
  • Signaling interactions in the adrenal cortex 
    Spät, András; Hunyady, László; Szanda Gergő (2016)
  • The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor 
    Turu, Gábor; Balla, András; Hunyady, László (2019)
    AT1 angiotensin receptor plays important physiological and pathophysiological roles in the cardiovascular system. Renin-angiotensin system represents a target system for drugs acting at different levels. The main effects ...