Folyóiratcikkek tallózása szerző szerint "Jordan Frank"

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A multipronged approach unravels unprecedented protein-protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

Zhou Jieyu; Yang Luying; Ozohanics Oliver; Zhang Xu; Wang Junjie; Ambrus, Attila; Arjunan Palaniappa; Brukh Roman; Nemeria Natalia S; Furey William; Jordan Frank (2018)

The human 2-oxoglutaric acid dehydrogenase complex (hOGDHc) plays a pivotal role in the tricarboxylic acid (TCA) cycle, and its diminished activity is associated with neurodegenerative diseases. The hOGDHc comprises three ...
Structural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry: Implications for the structural basis of E3 deficiency

Ambrus, Attila; Wang Junjie; Mizsei, Réka; Zámbó, Zsófia; Törőcsik, Beáta; Jordan Frank; Ádám-Vizi, Veronika (2016)

Pathogenic amino acid substitutions of the common E3 component (hE3) of the human alpha-ketoglutarate dehydrogenase and the pyruvate dehydrogenase complexes lead to severe metabolic diseases (E3 deficiency), which usually ...

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