Folyóiratcikkek tallózása szerző szerint "Ruppert, Mihály"

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Acute canagliflozin treatment protects against in vivo myocardial ischemia-reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation

Sayour, Alex Ali; Korkmaz-Icoez, Sevil; Loganathan, Sivakkanan; Ruppert, Mihály; Sayour, Viktor Nabil; Oláh, Attila; Benke, Kálmán; Brune, Maik; Benkő, Rita; Horvath, Eszter Mária; Karck, Matthias; Merkely, Béla Péter; Radovits, Tamás; Szabo, Gabor (2019)
Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes

Korkmaz-Icoz S; Atmanli A; Radovits, Tamás; Li S; Hegedus P; Ruppert, Mihály; Brlecic P; Yoshikawa Y; Yasui H; Karck M; Szabó, Gábor Balázs (2016)

We recently demonstrated that the pre-treatment of rats with zinc and acetylsalicylic acid complex in the form of bis(aspirinato)zinc(II) [Zn(ASA)2] is superior to acetylsalicylic acid in protecting the heart from acute ...
Cardiac effects of acute exhaustive exercise in a rat model

Oláh, Attila; Németh, Balázs Tamás; Mátyás, Csaba; Horvath, Eszter Mária; Hidi, László; Birtalan, Ede; Kellermayer, Dalma; Ruppert, Mihály; Merkely, Gergő; Szabó, Gábor Balázs; Merkely, Béla Péter; Radovits, Tamás (2015)
Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload

Németh, Balázs Tamás; Mátyás, Csaba; Oláh, Attila; Lux, Árpád; Hidi, László; Ruppert, Mihály; Kellermayer, Dalma; Kökény, Gábor; Szabó, Gábor Balázs; Merkely, Béla Péter; Radovits, Tamás (2016)

Pathologic myocardial hypertrophy develops when the heart is chronically pressure-overloaded. Elevated intracellular cGMP-levels have been reported to prevent the development of pathologic myocardial hypertrophy, therefore ...
Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

Mátyás, Csaba; Kovács, Attila; Németh, Balázs Tamás; Oláh, Attila; Braun Szilveszter; Tokodi, Márton; Barta, Bálint András; Benke, Kálmán; Ruppert, Mihály; Lakatos, Bálint; Merkely, Béla Péter; Radovits, Tamás (2018)

BACKGROUND: Measurement of systolic and diastolic function in animal models is challenging by conventional non-invasive methods. Therefore, we aimed at comparing speckle-tracking echocardiography (STE)-derived parameters ...
Comparison of the Reverse-Remodeling Effect of Pharmacological Soluble Guanylate Cyclase Activation With Pressure Unloading in Pathological Myocardial Left Ventricular Hypertrophy

Ruppert, Mihály; Korkmaz-Icöz, Sevil; Li, Shiliang; Brlecic, Paige; Németh, Balázs Tamás; Oláh, Attila; Horváth, Eszter M; Veres, Gábor; Pleger, Sven; Grabe, Niels; Merkely, Béla; Karck, Matthias; Radovits, Tamás; Szabó, Gábor (2019)

Background: Pressure unloading induces the regression of left ventricular myocardial hypertrophy (LVH). Recent findings indicate that pharmacological activation of the soluble guanylate cyclase (sGC) - cyclic guanosine ...
Mild Type 2 Diabetes Mellitus Reduces the Susceptibility of the Heart to Ischemia/Reperfusion Injury: Identification of Underlying Gene Expression Changes.

Korkmaz-Icoz S; Lehner A; Li S; Vater A; Radovits, Tamás; Hegedűs, Péter; Ruppert, Mihály; Brlecic P; Zorn M; Karck M; Szabó, Gábor Balázs (2015)

Despite clinical studies indicating that diabetic hearts are more sensitive to ischemia/reperfusion injury, experimental data is contradictory. Although mild diabetes prior to ischemia/reperfusion may induce a myocardial ...
Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway.

Korkmaz-Icoz S; Al Said S; Radovits, Tamás; Li S; Brune M; Hegedus P; Atmanli A; Ruppert, Mihály; Brlecic P; Lehmann LH; Lahrmann B; Grabe N; Yoshikawa Y; Yasui H; Most P; Karck M; Szabó, Gábor Balázs (2016)

BACKGROUND: Type-2 diabetics have an increased risk of cardiomyopathy, and heart failure is a major cause of death among these patients. Growing evidence indicates that proinflammatory cytokines may induce the development ...
Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation

Benke, Kálmán; Mátyás, Csaba; Sayour AA; Oláh, Attila; Németh, Balázs Tamás; Ruppert, Mihály; Szabo G; Kökény, Gábor; Horvath, Eszter Mária; Hartyánszky, István; Szabolcs, Zoltán; Merkely, Béla Péter; Radovits, Tamás (2017)

While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate cyclase (sGC) and increased cGMP-signalling have been reported to ...
Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes

Mátyás, Csaba; Németh, Balázs Tamás; Oláh, Attila; Török, Marianna; Ruppert, Mihály; Kellermayer, Dalma; Barta BA; Szabó, Gábor Balázs; Kökény, Gábor; Horvath, Eszter Mária; Bódi, Beáta; Papp, Zoltán; Merkely, Béla Péter; Radovits, Tamás (2017)

AIMS: Heart failure with preserved ejection fraction (HFpEF) has a great epidemiological burden. The pathophysiological role of cyclic guanosine monophosphate (cGMP) signalling has been intensively investigated in HFpEF. ...
The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus

Mátyás, Csaba; Németh, Balázs Tamás; Oláh, Attila; Hidi, László; Birtalan, Ede; Kellermayer, Dalma; Ruppert, Mihály; Korkmaz-Icoz S; Kökény, Gábor; Horvath, Eszter Mária; Szabó, Gábor Balázs; Merkely, Béla Péter; Radovits, Tamás (2015)

BACKGROUND: Diabetes mellitus (DM) leads to the development of diabetic cardiomyopathy, which is associated with altered nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) signalling. ...

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Folyóiratcikkek tallózása szerző szerint "Ruppert, Mihály"

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