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dc.contributor.author Dósa, Edit
dc.contributor.author Hirschberg K
dc.contributor.author Apor, Astrid
dc.contributor.author Járányi, Zsuzsanna
dc.contributor.author Entz, László
dc.contributor.author Acsády, György
dc.contributor.author Hüttl, Kálmán
dc.date.accessioned 2016-04-08T11:10:20Z
dc.date.available 2016-04-08T11:10:20Z
dc.date.issued 2010
dc.identifier 75149191879
dc.identifier.citation pagination=345-350; journalVolume=51; journalIssueNumber=2; journalTitle=JOURNAL OF VASCULAR SURGERY;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/2617
dc.identifier.uri doi:10.1016/j.jvs.2009.08.080
dc.description.abstract OBJECTIVE: Although the association between vulnerable lesions and cardiovascular events is well established, little is known about their relationship to postsurgery restenosis. To address this issue, we initiated a prospective, nonrandomized study to examine the femoral plaques on both sides in patients who were undergoing eversion carotid endarterectomy (CEA) and were longitudinally followed-up for early restenosis development. METHODS: The final analysis enrolled 321 patients (189 women) with a median age of 67.0 years (interquartile range, 59.0-73.0 years), who underwent eversion CEA (2005 to 2007). Using duplex ultrasound scanning, we evaluated 321 common femoral atherosclerotic lesions on the day before CEA. A quantitative scale was used to grade the size of plaques as grade 1, one or more small plaques (<20 mm2); grade 2, moderate to large plaques; and grade 3, plaques giving flow disturbances. The plaque morphology in terms of echogenicity was graded as echolucent, 1; predominantly echolucent, 2; predominantly echogenic, 3; echogenic 4; or calcified, 5. The plaque surface was categorized as smooth, irregular, or ulcerated. The patients underwent carotid duplex ultrasound imaging at 6 weeks and at 6, 12, and 24 months after CEA. Mann-Whitney U test, chi2 test, and multivariate logistic regression were used for statistical evaluation. RESULTS: Internal carotid artery restenosis of > or = 50% was detected in 33 patients (10.28%) in the operated region. Neither the size (grade 1, P = .793; grade 2, P = .540; grade 3, P = .395) nor the surface characteristics of the femoral plaques (smooth, P = .278; irregular, P = .281; ulcerated, P = .934) were significantly different between the patients with and without carotid restenosis. Echolucent-predominantly echolucent femoral lesions were an independent predictor of recurrent carotid stenosis (adjusted odds ratio, 5.63; 95% confidence interval, 2.14-10.89; P < .001). CONCLUSION: Ultrasound evaluation of femoral plaque morphology before CEA can be useful for identifying patients at higher risk for carotid restenosis.
dc.relation.ispartof urn:issn:0741-5214
dc.title Echolucent or predominantly echolucent femoral plaques predict early restenosis after eversion carotid endarterectomy.
dc.type Journal Article
dc.date.updated 2015-11-24T10:28:30Z
dc.language.rfc3066 en
dc.identifier.mtmt 1619074
dc.identifier.wos 000274602800010
dc.identifier.pubmed 20141957
dc.contributor.department SE/AOK/K/Érsebészeti Klinika [2011.12.31]
dc.contributor.department SE/AOK/K/Kardiológia Központ - Kardiológiai Tanszék [2011.12.31]
dc.contributor.institution Semmelweis Egyetem


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