In vivo measurement of intragastric pressure with a rubber balloon in the anesthetized rat.

dc.contributor.author	Zádori Zoltán Sándor
dc.contributor.author	Gyires Klára
dc.date.accessioned	2016-01-28T09:10:42Z
dc.date.available	2016-01-28T09:10:42Z
dc.date.issued	2013
dc.identifier.citation	pagination=21.12.1-6.17.11.; journalVolume=57; journalTitle=CURRENT PROTOCOLS IN TOXICOLOGY;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/2710
dc.identifier.uri	doi:10.1002/0471140856.tx2112s57
dc.description.abstract	The protocols described in this unit are designed to measure the intragastric pressure in anesthetized rats by a water-filled low-compliance rubber balloon. The balloon is introduced into the stomach either orally (by passing the balloon down the esophagus) or directly via a small incision of the fundus after laparotomy. The effects of both stimulatory (e.g., carbachol) and inhibitory (e.g., oxymetazoline) agents can be evaluated on the gastric tone and phasic contractions. The model allows the evaluation of dose-response curves and also the time-course of the effects. Furthermore, by combining centrally or peripherally acting agents the site of action can also be determined. Curr. Protoc. Toxicol. 57:21.12.1-21.12.11. (c) 2013 by John Wiley & Sons, Inc.
dc.relation.ispartof	urn:issn:1934-9254
dc.title	In vivo measurement of intragastric pressure with a rubber balloon in the anesthetized rat.
dc.type	Journal Article
dc.date.updated	2015-11-25T10:22:40Z
dc.language.rfc3066	en
dc.identifier.mtmt	2527878
dc.identifier.pubmed	24510509
dc.contributor.department	SE/AOK/I/Farmakológiai és Farmakoterápiás Intézet
dc.contributor.institution	Semmelweis Egyetem