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dc.contributor.author Marton, Nikolett
dc.contributor.author Baricza, Eszter
dc.contributor.author Molnár-Érsek, Barbara
dc.contributor.author Buzás, Edit Irén
dc.contributor.author Nagy, György
dc.date.accessioned 2017-06-27T09:26:04Z
dc.date.available 2017-06-27T09:26:04Z
dc.date.issued 2015
dc.identifier 84939615547
dc.identifier.citation pagination=952536, 9 pages; journalVolume=2015; journalTitle=MEDIATORS OF INFLAMMATION;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/3014
dc.identifier.uri doi:10.1155/2015/952536
dc.description.abstract Although Src-like adaptor proteins (SLAP-1 and SLAP-2) were mainly studied in lymphocytes, where they act as negative regulators and provide fine control of receptor signaling, recently, several other functions of these proteins were discovered. In addition to the well-characterized immunoregulatory functions, SLAP proteins appear to have an essential role in the pathogenesis of type I hypersensitivity, osteoporosis, and numerous malignant diseases. Both adaptor proteins are expressed in a wide variety of tissues, where they have mostly inhibitory effects on multiple intracellular signaling pathways. In this review, we summarize the diverse effects of SLAP proteins.
dc.relation.ispartof urn:issn:0962-9351
dc.title The emerging and diverse roles of Src-like adaptor proteins in health and disease
dc.type Journal Article
dc.date.updated 2016-01-12T13:35:07Z
dc.language.rfc3066 en
dc.identifier.mtmt 2820907
dc.identifier.wos 000359582400001
dc.identifier.pubmed 26339145
dc.contributor.department SE/AOK/I/Genetikai, Sejt- és Immunbiológiai Intézet
dc.contributor.institution Semmelweis Egyetem
dc.mtmt.swordnote FELTÖLTŐ: Ádám Adrienn - adamadrienn78@gmail.com


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