dc.contributor.author |
van den Kieboom CH |
|
dc.contributor.author |
van der Beek SL |
|
dc.contributor.author |
Mészáros, Tamás |
|
dc.contributor.author |
Gyurcsányi, Ervin Róbert |
|
dc.contributor.author |
Ferwerda G |
|
dc.contributor.author |
de Jonge MI |
|
dc.date.accessioned |
2016-09-20T10:03:52Z |
|
dc.date.available |
2016-09-20T10:03:52Z |
|
dc.date.issued |
2015 |
|
dc.identifier |
84946070380 |
|
dc.identifier.citation |
pagination=58-67;
journalVolume=74;
journalTitle=TRAC-TRENDS IN ANALYTICAL CHEMISTRY; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/3026 |
|
dc.identifier.uri |
doi:10.1016/j.trac.2015.05.012 |
|
dc.description.abstract |
Novel viral diagnostic tools need to be affordable, fast,
accurate and easy to use with sensitivity and specificity
equivalent or superior to current standards. At present, viral
diagnostics are based on direct detection of viral components or
indirect detection by measuring antibodies generated in response
to viral infection. While sensitivity of detection and
quantification are still important challenges, we expect major
advances from new assay formats and synthetic binding molecules,
such as aptamers. Compared to traditional antibody-based
detection, aptamers could provide faster adaptation to
continuously evolving virus strains and higher discriminating
capacity between specific virus serotypes. Aptamers are very
stable and easily modifiable, so are ideal molecules for
detection and chemical sensing applications. Here, we review the
use of aptasensors for detection of viral pathogens and consider
the feasibility of aptasensors to become standard devices for
point-of-care diagnostics of viruses. © 2015. |
|
dc.relation.ispartof |
urn:issn:0165-9936 |
|
dc.title |
Aptasensors for viral diagnostics |
|
dc.type |
Journal Article |
|
dc.date.updated |
2016-01-20T15:37:03Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
2969421 |
|
dc.contributor.department |
BME/VBK/SZAKT/MTA-BME Műszaki Analitikai Kémiai Kutatócsoport |
|
dc.contributor.department |
BME/VBK/Szervetlen és Analitikai Kémia Tanszék |
|
dc.contributor.department |
SE/AOK/I/Orvosi Vegytani, Molekuláris Biológiai és Patobiokémiai Intézet |
|
dc.contributor.institution |
Budapesti Műszaki és Gazdaságtudományi Egyetem |
|
dc.contributor.institution |
Semmelweis Egyetem |
|
dc.mtmt.swordnote |
FELTÖLTŐ: Sonnevend Kinga - kinga.sonnevend@eok.sote.hu |
|