Association of some rare haplotypes and genotype combinations in the MDR1 gene with childhood acute lymphoblastic leukaemia.

dc.contributor.author	Semsei, Ágnes F
dc.contributor.author	Erdélyi, Dániel
dc.contributor.author	Ungvári, Ildikó
dc.contributor.author	Kamory E
dc.contributor.author	Csokay B
dc.contributor.author	Andrikovics, Hajnalka
dc.contributor.author	Csagoly E
dc.contributor.author	Tordai, Attila
dc.contributor.author	Falus, András
dc.contributor.author	Kovács, Gábor
dc.contributor.author	Szalai, Csaba
dc.date.accessioned	2018-10-12T10:58:03Z
dc.date.available	2018-10-12T10:58:03Z
dc.date.issued	2008
dc.identifier	42749084582
dc.identifier.citation	pagination=1214-1220; journalVolume=32; journalIssueNumber=8; journalTitle=LEUKEMIA RESEARCH;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/4783
dc.identifier.uri	doi:10.1016/j.leukres.2007.12.009
dc.description.abstract	To investigate their possible roles in disease susceptibility and some disease characteristics we genotyped C3435T and G2677T/A polymorphisms in multidrug resistance-1 (MDR1) gene with a single base extension method and the G34A and C421A polymorphisms of the breast cancer resistance protein gene with an allelic discrimination system in 396 children with acute lymphoblastic leukaemia (ALL) and 192 control patients. While the distribution of individual alleles and genotypes did not differ between patients and controls, there were significant differences in the frequencies of some rare haplotypes and genotype combinations in the MDR1 gene between the two groups.
dc.relation.ispartof	urn:issn:0145-2126
dc.title	Association of some rare haplotypes and genotype combinations in the MDR1 gene with childhood acute lymphoblastic leukaemia.
dc.type	Journal Article
dc.date.updated	2018-02-14T13:18:23Z
dc.language.rfc3066	en
dc.identifier.mtmt	1176176
dc.identifier.wos	000256251500008
dc.identifier.pubmed	18243305
dc.contributor.department	SE/AOK/K/II. Sz. Gyermekgyógyászati Klinika
dc.contributor.institution	Semmelweis Egyetem