Egyszerű nézet Czakó Cecilia Nóra Sándor Gábor László Ecsedy Mónika Szepessy Zsuzsanna Borbándy Ágnes Resch Miklós Papp András Récsán Zsuzsanna Horváth Hajnalka Nagy Zoltán Zsolt Kovács Illés 2018-03-11T16:52:21Z 2018-03-11T16:52:21Z 2018
dc.identifier.citation pagination=320-326; journalVolume=159; journalIssueNumber=8; journalTitle=ORVOSI HETILAP;
dc.identifier.uri doi:10.1556/650.2018.30962
dc.description.abstract INTRODUCTION: Optical coherence tomography angiography is a non-invasive imaging technique that is able to visualize the different retinal vascular layers using motion contrast to detect blood flow without intravenous dye injection. This method might help to assess microangiopathy in diabetic retinopathy during screening and follow-up. AIM: To quantify retinal microvasculature alterations in both eyes of diabetic patients in relation to systemic risk factors using optical coherence tomography angiography. METHOD: Both eyes of 36 diabetic patients and 45 individuals without diabetes were examined. Duration of diabetes, insulin therapy, blood pressure, HbA1c, dyslipidemia, axial length and the presence of diabetic retinopathy were recorded. Retinal vessel density was measured by optical coherence tomography angiography. The effect of risk factors on vessel density and between-eye asymmetry was assessed using multivariable regression analysis. RESULTS: Vessel density was significantly lower and between-eye difference was significantly higher in diabetic patients compared to controls (p<0.05). Both vessel density and between-eye asymmetry significantly correlated with diabetes duration (p<0.05) after controlling for the effect of risk factors. The between-eye asymmetry in vessel density was significantly higher in patients without clinically detectable diabetic retinopathy compared to control subjects (p<0.001). CONCLUSIONS: There is a decrease in retinal vessel density and an increase in between-eye asymmetry in patients with diabetes compared to healthy subjects. By using optical coherence tomography angiography, the detection of these microvascular alterations is possible before clinically detectable diabetic retinopathy and might serve as a useful tool in both screening and timing of treatment. Orv Hetil. 2018; 159(8): 320-326.
dc.relation.ispartof urn:issn:0030-6002
dc.title Diabeteses kiser-karosodas vizsgalata optikai koherencia tomografian alapulo angiografiaval.
dc.type Journal Article 2018-03-11T16:50:53Z
dc.language.rfc3066 hu
dc.identifier.mtmt 3338708
dc.identifier.pubmed 29429361
dc.contributor.department SE/AOK/K/Szemészeti Klinika
dc.contributor.institution Semmelweis Egyetem

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