dc.contributor.author |
Bugyik, Edina |
|
dc.contributor.author |
Rényi-Vámos, Ferenc István |
|
dc.contributor.author |
Szabó, Vanessza |
|
dc.contributor.author |
Dezső, Katalin |
|
dc.contributor.author |
Ecker N |
|
dc.contributor.author |
Rókusz, András |
|
dc.contributor.author |
Nagy, Péter |
|
dc.contributor.author |
Döme, Balázs |
|
dc.contributor.author |
Paku, Sándor |
|
dc.date.accessioned |
2018-06-27T12:01:10Z |
|
dc.date.available |
2018-06-27T12:01:10Z |
|
dc.date.issued |
2016 |
|
dc.identifier |
84959534201 |
|
dc.identifier.citation |
pagination=19, pages: 8;
journalVolume=35;
journalIssueNumber=1;
journalTitle=CHINESE JOURNAL OF CANCER; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/5542 |
|
dc.identifier.uri |
doi:10.1186/s40880-016-0083-5 |
|
dc.description.abstract |
Directed capillary ingrowth has long been considered synonymous with tumor vascularization. However, the vasculature of primary tumors and metastases is not necessarily formed by endothelial cell sprouting; instead, malignant tumors can acquire blood vessels via alternative vascularization mechanisms, such as intussusceptive microvascular growth, vessel co-option, and glomeruloid angiogenesis. Importantly, in response to anti-angiogenic therapies, malignant tumors can switch from one vascularization mechanism to another. In this article, we briefly review the biological features of these mechanisms and discuss on their significance in medical oncology. |
|
dc.relation.ispartof |
urn:issn:1000-467X |
|
dc.title |
Mechanisms of vascularization in murine models of primary and metastatic tumor growth |
|
dc.type |
Journal Article |
|
dc.date.updated |
2018-06-06T12:20:25Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
3022927 |
|
dc.identifier.wos |
000370009300002 |
|
dc.identifier.pubmed |
26873579 |
|
dc.contributor.department |
SE/AOK/K/Mellkassebészeti Klinika |
|
dc.contributor.department |
SE/AOK/I/IISZPI/MTA-SE Molekuláris Onkológia Kutatócsoport |
|
dc.contributor.department |
SE/AOK/I/I. Sz. Patológiai és Kísérleti Rákkutató Intézet |
|
dc.contributor.institution |
Semmelweis Egyetem |
|
dc.mtmt.swordnote |
Edina Bugyik and Ferenc Renyi-Vamos contributed equally as
first authors to this study. |
|