Spiegelmers as potential receptors for cTnI diagnostics

dc.contributor.author	Szeitner, Zsuzsanna
dc.contributor.author	Doleschall Anna,
dc.contributor.author	Varga, Marina
dc.contributor.author	Keltai, Katalin
dc.contributor.author	Révész, Katalin
dc.contributor.author	Gyurcsányi, Ervin Róbert
dc.contributor.author	Mészáros, Tamás
dc.date.accessioned	2022-04-26T08:47:45Z
dc.date.available	2022-04-26T08:47:45Z
dc.date.issued	2017
dc.identifier	85029414714
dc.identifier.citation	pagination=5091-5093; journalVolume=9; journalIssueNumber=35; journalTitle=ANALYTICAL METHODS: ADVANCING METHODS AND APPLICATIONS;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/5582
dc.identifier.uri	doi:10.1039/C7AY01777D
dc.description.abstract	We demonstrate the first application of a nuclease resistant aptamer, the so-called Spiegelmer, in a sandwich-type affinity assay by quantitative assessment of cardiac Troponin I (cTnI) in blood serum samples. To this end, we used a bead-based homogenous proximity assay (AlphaLISA) in which luminescence is generated by the Spiegelmer and antibody-modified donor and acceptor beads brought into proximity by their binding to cTnI.
dc.relation.ispartof	urn:issn:1759-9660
dc.title	Spiegelmers as potential receptors for cTnI diagnostics
dc.type	Journal Article
dc.date.updated	2018-06-08T11:45:08Z
dc.language.rfc3066	en
dc.identifier.mtmt	3266150
dc.identifier.wos	000411529300002
dc.identifier.scopus	85029414714
dc.contributor.department	BME/VBK/SZAKT/MTA-BME Lendület Kémiai Nanoérzékelők Kutatócsoport
dc.contributor.department	BME/VBK/Szervetlen és Analitikai Kémia Tanszék
dc.contributor.department	BME/VBK/SZAKT/MTA-BME Műszaki Analitikai Kémiai Kutatócsoport
dc.contributor.institution	Budapesti Műszaki és Gazdaságtudományi Egyetem