Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy

dc.contributor.author	Kosztin, Annamária
dc.contributor.author	Széplaki, Gábor
dc.contributor.author	Kovács, Attila
dc.contributor.author	Földes, Gábor
dc.contributor.author	Szokodi, István
dc.contributor.author	Nagy, Klaudia Vivien
dc.contributor.author	Kutyifa, Valentina
dc.contributor.author	Forizs E
dc.contributor.author	Végh, Eszter Mária
dc.contributor.author	Gellér, László Alajos
dc.contributor.author	Becker, Dávid
dc.contributor.author	Aradi, Dániel
dc.contributor.author	Merkely, Béla Péter
dc.date.accessioned	2018-09-04T11:50:50Z
dc.date.available	2018-09-04T11:50:50Z
dc.date.issued	2017
dc.identifier	84981725149
dc.identifier.citation	pagination=279-286; journalVolume=22; journalIssueNumber=3-4; journalTitle=BIOMARKERS;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/5771
dc.identifier.uri	doi:10.1080/1354750X.2016.1217931
dc.description.abstract	CONTEXT: Assessment of response to cardiac resynchronization therapy (CRT) is essential. OBJECTIVE: To assess the predictive value of CT-apelin together with NT-proBNP in patients undergoing CRT. METHODS: Serum CT-apelin and NT-proBNP were measured by ELISA before, and 6-month after CRT. Primary endpoint was non-response (<4% increase in LVEF) after 6-month. RESULTS: From 81 patients, 15 proved to be non-responders. Six-month CT-apelin was superior compared to NT-proBNP in identifying non-responders by multivariate ROC (CT-apelin:p = 0.01, NT-proBNP:p = 0.13) and by logistic regression (CT-apelin:p = 0.01, NT-proBNP:p = 0.41) analyzes. CONCLUSION: Six-month CT-apelin might be valuable novel biomarker in identifying non-responders to CRT that was superior to NT-proBNP.
dc.relation.ispartof	urn:issn:1354-750X
dc.title	Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy
dc.type	Journal Article
dc.date.updated	2018-07-13T06:45:17Z
dc.language.rfc3066	en
dc.identifier.mtmt	3097560
dc.identifier.wos	000399649800012
dc.identifier.pubmed	27471876
dc.contributor.department	SE/AOK/K/VAROSMAJOR_SZÍVÉRGYÓGY/Kardiológia Központ - Kardiológiai Tanszék [2017.10.31]
dc.contributor.department	SE/AOK/K/Városmajori Szív- és Érgyógyászati Klinika
dc.contributor.institution	Semmelweis Egyetem
dc.mtmt.swordnote	Megosztott elsőszerzőség Kosztin A és Szeplaki G között