dc.contributor.author |
Fancsovits, Péter |
|
dc.contributor.author |
Urbancsek, János Attila |
|
dc.contributor.author |
Fónyad, László |
|
dc.contributor.author |
Sebestyén, Anna |
|
dc.contributor.author |
Csorba G |
|
dc.contributor.author |
Lehner, Ádám |
|
dc.contributor.author |
Kaszás, Zita |
|
dc.contributor.author |
Rigó, János |
|
dc.contributor.author |
Bokor, Attila |
|
dc.date.accessioned |
2018-10-01T09:21:07Z |
|
dc.date.available |
2018-10-01T09:21:07Z |
|
dc.date.issued |
2016 |
|
dc.identifier |
85006041885 |
|
dc.identifier.citation |
pagination=1947-1954;
journalVolume=157;
journalIssueNumber=49;
journalTitle=ORVOSI HETILAP; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/5862 |
|
dc.identifier.uri |
doi:10.1556/650.2016.30582 |
|
dc.description.abstract |
INTRODUCTION: The oncological treatment may damage ovarian function. To prevent this, it is possible to cryopreserve the ovarian tissue, and to keep the samples for long-term storage. The frozen-thawed tissue could be retransplanted after chemo- or radiotherapy. AIM: The aim of our study was to examine the effect of cryopreservation on the viability of ovarian tissue. METHOD: We analyzed the survival of frozen-thawed donated ovarian tissues. The quality of the follicles and hormone production in fresh and frozen-thawed samples were compared. RESULTS: Histological analysis showed that the number of viable follicles was reduced by 23% in the frozen-thawed samples. However, viable follicles still presented in post thawing ovarian tissues. Maximal estradiol production in frozen-thawed tissues was 908 pg/ml and hormone production was similar to the control tissues. The maximal progesterone production was 1.95 ng/ml post thawing, but these values were lower than the progesterone production of fresh tissues. CONCLUSIONS: The method of ovarian cryopreservation used in our laboratory was able preserve the viability of follicles in frozen-thawed ovarian tissues. Orv. Hetil., 2016, 157(49), 1947-1954. |
|
dc.relation.ispartof |
urn:issn:0030-6002 |
|
dc.title |
Kezdeti tapasztalataink a petefészekszövet-fagyasztás bevezetésével. [First attempts in the introduction of cryopreservation of ovarian tissues] |
|
dc.type |
Journal Article |
|
dc.date.updated |
2018-07-16T13:31:52Z |
|
dc.language.rfc3066 |
hu |
|
dc.identifier.mtmt |
3151734 |
|
dc.identifier.wos |
000389882600002 |
|
dc.identifier.pubmed |
27917673 |
|
dc.contributor.department |
SE/AOK/K/I. Sz. Szülészeti és Nőgyógyászati Klinika |
|
dc.contributor.department |
SE/AOK/I/I. Sz. Patológiai és Kísérleti Rákkutató Intézet |
|
dc.contributor.institution |
Semmelweis Egyetem |
|