dc.contributor.author |
Engel-Yeger B, |
|
dc.contributor.author |
Gonda, Xénia |
|
dc.contributor.author |
Canepa G, |
|
dc.contributor.author |
Pompili M, |
|
dc.contributor.author |
Rihmer, Zoltán |
|
dc.contributor.author |
Amore M |
|
dc.contributor.author |
Serafini G |
|
dc.date.accessioned |
2018-09-01T13:00:29Z |
|
dc.date.available |
2018-09-01T13:00:29Z |
|
dc.date.issued |
2018 |
|
dc.identifier |
85028509612 |
|
dc.identifier.citation |
pagination=466-473;
journalVolume=225;
journalTitle=JOURNAL OF AFFECTIVE DISORDERS; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/6326 |
|
dc.identifier.uri |
doi:10.1016/j.jad.2017.08.036 |
|
dc.description.abstract |
INTRODUCTION: Extreme sensory processing patterns may contribute to the pathophysiology of major affective disorders. We aimed to examine whether significant correlations exist between sensory profiles, hypomania, self-reported depression, and hopelessness and whether sensory profiles may be potential mediators of the association between hypomania and depression/hopelessness. METHODS: The sample consisted of 488 euthymic affective disorder patients of which 283 diagnosed with unipolar and 162 with bipolar disorder with an age ranging from 18 to 65 years (mean = 47.82 +/- 11.67). RESULTS: Lower registration of sensory input and sensory sensitivity significantly correlated with elevated self-reported depression, hopelessness, and irritable/risk-taking hypomania while sensation seeking and avoiding significantly correlated with elevated depression and hopelessness but not with irritable/risk-taking hypomania. Moreover, individuals with lower ability to register sensory input and higher hypomania showed higher self-reported depression than those with good registration of sensory information. According to SEM analyses, there was both a direct/indirect effect of irritable/risk-taking on depression-hopelessness with the mediation model explaining 48% of the variance in depression-hopelessness. LIMITATIONS: The relatively small sample size and the cross-sectional nature of the study design do not allow the generalization of the main findings. CONCLUSION: Low registration was associated with enhanced depressed mood and hopelessness while sensory seeking may be considered a resilient factor. |
|
dc.relation.ispartof |
urn:issn:0165-0327 |
|
dc.title |
Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients. |
|
dc.type |
Journal Article |
|
dc.date.updated |
2018-09-01T11:36:07Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
3285897 |
|
dc.identifier.wos |
WOS:000413405700067 |
|
dc.identifier.pubmed |
28863299 |
|
dc.contributor.department |
SE/GYTK/Gyógyszerhatástani Intézet |
|
dc.contributor.department |
SE/GYTK/GYHATAS/MTA-SE Neuropszichofarmakológiai és Neurokémiai Kutatócsoport |
|
dc.contributor.department |
SE/AOK/K/Pszichiátriai és Pszichoterápiás Klinika |
|
dc.contributor.institution |
Semmelweis Egyetem |
|
dc.contributor.institution |
Semmelweis Egyetem |
|