dc.contributor.author |
Kokonyei Gyongyi |
|
dc.contributor.author |
Galambos Attila |
|
dc.contributor.author |
Edes Andrea Edit |
|
dc.contributor.author |
Kocsel Natalia |
|
dc.contributor.author |
Szabo Edina |
|
dc.contributor.author |
Pap Dorottya |
|
dc.contributor.author |
Kozak, Lajos R |
|
dc.contributor.author |
Bagdy Gyorgy |
|
dc.contributor.author |
Juhasz Gabriella |
|
dc.date.accessioned |
2019-06-29T18:38:16Z |
|
dc.date.available |
2019-06-29T18:38:16Z |
|
dc.date.issued |
2019 |
|
dc.identifier |
85053830548 |
|
dc.identifier.citation |
pagination=56-72;
journalVolume=19;
journalIssueNumber=1;
journalTitle=COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE;
journalAbbreviatedTitle=COGN AFFECT BEHAV NE; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/7095 |
|
dc.identifier.uri |
doi:10.3758/s13415-018-0644-y |
|
dc.description.abstract |
Rumination - as a stable tendency to focus repetitively on feelings related to distress - represents a transdiagnostic risk factor. Theories suggest altered emotional information processing as the key mechanism of rumination. However, studies on the anticipation processes in relation to rumination are scarce, even though expectation in this process is demonstrated to influence the processing of emotional stimuli. In addition, no published study has investigated violated expectation in relation to rumination yet. In the present study we examined the neural correlates of pain anticipation and perception using a fear conditioning paradigm with pain as the unconditioned stimulus in healthy subjects (N = 30). Rumination was assessed with the 10-item Ruminative Response Scale (RRS). Widespread brain activation - extending to temporal, parietal, and occipital lobes along with activation in the cingulate cortex, insula, and putamen - showed a positive correlation with rumination, supporting our hypothesis that trait rumination influences anticipatory processes. Interestingly, with violated expectation (when an unexpected, non-painful stimulus follows a pain cue compared to when an expected, painful stimulus follows the same pain cue) a negative association between rumination and activation was found in the posterior cingulate cortex, which is responsible for change detection in the environment and subsequent behavioral modification. Our results suggest that rumination is associated with increased neural response to pain perception and pain anticipation, and may deteriorate the identification of an unexpected omission of aversive stimuli. Therefore, targeting rumination in cognitive behavioral therapy of chronic pain could have a beneficial effect. |
|
dc.format.extent |
56-72 |
|
dc.title |
Anticipation and violated expectation of pain are influenced by trait rumination |
|
dc.type |
Journal Article |
|
dc.date.updated |
2019-06-29T18:33:23Z |
|
dc.language.rfc3066 |
en |
|
dc.rights.holder |
NULL |
|
dc.identifier.mtmt |
30337751 |
|
dc.identifier.wos |
000456550100003 |
|
dc.identifier.pubmed |
30251186 |
|
dc.contributor.institution |
MTA-SE-NAP B Genetikai Agyi Képalkotó Migrén Kutató Csoport |
|
dc.contributor.institution |
Kognitív Idegtudományi és Pszichológiai Intézet |
|
dc.contributor.institution |
NAP-A-SE Új Antidepresszív Gyógyszercélpont Kutatócsoport |
|
dc.contributor.institution |
Klinikai Pszichológia és Addiktológia Tanszék |
|
dc.contributor.institution |
NAP-2-SE Új Antidepresszív Gyógyszercélpont Kutatócsoport |
|
dc.contributor.institution |
SE-NAP 2 Genetikai Agyi Képalkotó Migrén Kutatócsoport |
|
dc.contributor.institution |
PhD Pszichológiai Doktori Iskola |
|
dc.contributor.institution |
Semmelweis Egyetem |
|
dc.contributor.institution |
MR Kutatóközpont |
|
dc.contributor.institution |
MTA-SE Neuropszichofarmakológiai és Neurokémiai Kutatócsoport |
|
dc.contributor.institution |
Doktori Iskola |
|
dc.contributor.institution |
MTA-PPKE Infobionikai és Neurobiológiai Plaszticitás Kutatócsoport (2006-ig: MTA-SE Neurobiológiai Kutatócsoport) |
|
dc.contributor.institution |
Általános Orvostudományi Kar |
|
dc.contributor.institution |
Farmakológiai és Farmakoterápiás Intézet |
|
dc.contributor.institution |
MTA-SE Neuropszichofarmakológiai Kutatócsoport (2007-től társult tag) |
|
dc.contributor.institution |
Gyógyszerhatástani Intézet |
|
dc.contributor.institution |
Személyiség- és Egészségpszichológiai Tanszék |
|
dc.contributor.institution |
Klinikai Pszichológia és Addiktológia Tanszék |
|
dc.mtmt.swordnote |
SE-NAP2 Genetic Brain Imaging Migraine Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary
Institute of Psychology, ELTE Eötvös Loránd University, Izabella street 46, Budapest, H-1064, Hungary
Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary
Doctoral School of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary
MTA-SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary
MR Research Center, Semmelweis University, Budapest, Hungary
Neuroscience and Psychiatry Unit, The University of Manchester, Manchester, United Kingdom
Manchester Academic Health Sciences Centre, Manchester, United Kingdom
Export Date: 10 January 2019
Article in Press
CODEN: CABNC
Correspondence Address: Kokonyei, G.; Institute of Psychology, ELTE Eötvös Loránd University, Izabella street 46, Hungary; email: kokonyei.gyongyi@ppk.elte.hu |
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