dc.contributor.author |
Gecse, Krisztina |
|
dc.contributor.author |
Sebastian, S |
|
dc.contributor.author |
Hertogh, G |
|
dc.contributor.author |
Yassin, NA |
|
dc.contributor.author |
Kotze, PG |
|
dc.contributor.author |
Reinisch, W |
|
dc.contributor.author |
Spinelli, A |
|
dc.contributor.author |
Koutroubakis, IE |
|
dc.contributor.author |
Katsanos, KH |
|
dc.contributor.author |
Hart, A |
|
dc.contributor.author |
van den Brink, GR |
|
dc.contributor.author |
Rogler, G |
|
dc.contributor.author |
Bemelman, WA |
|
dc.date.accessioned |
2019-10-04T17:43:13Z |
|
dc.date.available |
2019-10-04T17:43:13Z |
|
dc.date.issued |
2016 |
|
dc.identifier.citation |
journalVolume=10;journalIssueNumber=7;journalTitle=JOURNAL OF CROHNS & COLITIS;pagerange=758-765;journalAbbreviatedTitle=J CROHNS COLITIS; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/7356 |
|
dc.identifier.uri |
doi:10.1093/ecco-jcc/jjw039 |
|
dc.description.abstract |
BACKGROUND AND AIMS: Perianal fistulas affect up to one-third of Crohn's patients during the course of their disease. Despite the considerable disease burden, current treatment options remain unsatisfactory. The Fifth Scientific Workshop [SWS5] of the European Crohn's and Colitis Organisation [ECCO] focused on the pathophysiology and clinical impact of fistulas in the disease course of patients with Crohn's disease [CD]. METHODS: The ECCO SWS5 Working Group on clinical aspects of perianal fistulising Crohn's disease [pCD] consisted of 13 participants, gastroenterologists, colorectal surgeons, and a histopathologist, with expertise in the field of inflammatory bowel diseases. A systematic review of literature was performed. RESULTS: Four main areas of interest were identified: natural history of pCD, morphological description of fistula tracts, outcome measures [including clinical and patient-reported outcome measures, as well as magnetic resonance imaging] and randomised controlled trials on pCD. CONCLUSIONS: The treatment of perianal fistulising Crohn's disease remains a multidisciplinary challenge. To optimise management, a reliable classification and proper trial endpoints are needed. This could lead to standardised diagnosis, treatment, and follow-up of Crohn's perianal fistulas and the execution of well-designed trials that provide clear answers. The prevalence and the natural history of pCD need further evaluation. |
|
dc.format.extent |
758-765 |
|
dc.relation.ispartof |
urn:issn: 1873-9946 1876-4479 |
|
dc.title |
Results of the Fifth Scientific Workshop of the ECCO [II]: Clinical Aspects of Perianal Fistulising Crohn's Disease-the Unmet Needs. |
|
dc.type |
Journal Article |
|
dc.date.updated |
2019-07-30T10:52:42Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
3060396 |
|
dc.identifier.wos |
000379765800002 |
|
dc.identifier.scopus |
85012141294 |
|
dc.identifier.pubmed |
26826183 |
|
dc.contributor.department |
SE/AOK/K/I. Sz. Belgyógyászati Klinika |
|
dc.contributor.institution |
I. Sz. Belgyógyászati Klinika |
|
dc.contributor.institution |
Semmelweis Egyetem |
|