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dc.contributor.author Vingender, Szonja
dc.contributor.author Restár, László
dc.contributor.author Csomó, Krisztián Benedek
dc.contributor.author Schmidt, Péter
dc.contributor.author Hermann, Péter
dc.contributor.author Vaszilkó, Mihály
dc.date.accessioned 2021-09-20T06:46:48Z
dc.date.available 2021-09-20T06:46:48Z
dc.date.issued 2018
dc.identifier 85052714515
dc.identifier.citation journalVolume=159;journalIssueNumber=36;journalTitle=ORVOSI HETILAP;pagerange=1475-1482;journalAbbreviatedTitle=ORV HETIL;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/7485
dc.identifier.uri doi:10.1556/650.2018.31138
dc.description.abstract INTRODUCTION: Derangement of the temporomandibular joint complicates everyday life, due to the masticatory malfunction and the continuous pain sensation of the head and facial region. The therapy is multidisciplinary and varying. In case of the inefficiency of conservative therapy, minimally invasive intervention is needed with intraarticular injection. AIM: The aim of our study was to examine whether hyaluronic acid injection is more beneficial compared to corticosteroid in 37 joints. We also examined whether the efficacy of the therapy is influenced by hyaluronic acid molecular weight and the used protocol. METHOD: Wilkes stage, maximal mouth opening and the Visual Analogue Scale were determined pre-operatively and 6 months later. Corticosteroid application was performed once, hyaluronic acid was injected on a weekly bases 3 times in a row, by use of low (6-10 x 10(5) dalton) or high molecular weight (24-36 x 10(5) dalton) preparations. RESULTS: The medical state of the patients treated with corticosteroid temporarily improved, but the symptoms returned. Due to hyaluronic acid treatment, significant improvement was revealed in all parameters (pwilkes<0.0001; pmouth-opening = 0.0002; pVAS<0.0001). There was no significant relapse (T = 2.05). The third administration of hyaluronic acid resulted in a significant improvement of the Visual Analogue Scale compared to the first and second injection (T3.-1. = 20.37; T3.-2. = 9.57). CONCLUSIONS: Comparing the two agents we can state that hyaluronic acid was significantly more effective and its application for three times seems to be the most effective treatment decreasing the symptoms. The high molecular weight solution was more effective in increasing mouth opening. In contrast to hyaluronic acid, corticosteroid had no prolonged effect in higher Wilkes stages. Orv Hetil. 2018; 159(36): 1475-1482.
dc.format.extent 1475-1482
dc.relation.ispartof urn:issn:0030-6002 1788-6120
dc.title Az állkapocsízületi károsodás kezelése szteroiddal, illetve hialuronsavval.
dc.type Journal Article
dc.date.updated 2019-08-16T19:06:16Z
dc.language.rfc3066 hu
dc.rights.holder NULL
dc.identifier.mtmt 3418162
dc.identifier.wos 000443391800003
dc.identifier.scopus 85052714515
dc.identifier.pubmed 30175606
dc.contributor.department SE/FOK/Arc- Állcsont- Szájsebészeti és Fogászati Klinika
dc.contributor.department SE/FOK/Fogpótlástani Klinika
dc.contributor.department SE/FOK/Orális Diagnosztikai Tanszék
dc.contributor.institution Semmelweis Egyetem


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