Plasma VEGF levels and their relation to right ventricular function in pulmonary hypertension

dc.contributor.author	Pákó, Judit Erzsébet
dc.contributor.author	Bikov, András
dc.contributor.author	Karlócai, Kristóf
dc.contributor.author	Csósza, Györgyi
dc.contributor.author	Kunos, László
dc.contributor.author	Losonczy, György
dc.contributor.author	Horváth, Ildikó
dc.date.accessioned	2021-04-06T11:30:15Z
dc.date.available	2021-04-06T11:30:15Z
dc.date.issued	2015
dc.identifier	84943544277
dc.identifier.citation	journalVolume=37;journalIssueNumber=4;journalTitle=CLINICAL AND EXPERIMENTAL HYPERTENSION;pagerange=340-344;journalAbbreviatedTitle=CLIN EXP HYPERTENS;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/7754
dc.identifier.uri	doi:10.3109/10641963.2014.972561
dc.description.abstract	Abstract A protective role of vascular endothelial growth factor (VEGF) on right heart function has been reported only in animal studies of pulmonary hypertension. Twenty patients with idiopathic pulmonary hypertension and fifteen healthy volunteers were involved. Plasma VEGF levels were compared to right heart parameters. Plasma VEGF levels tended to be higher in patients (82/0-345/pg/ml) than in controls (48/0-141/pg/ml, p = 0.08) with a significant correlation between VEGF concentration and tricuspid annular plane systolic excursion (TAPSE; p = 0.03, r = 0.48). This is the first study to report a positive association between elevated plasma VEGF levels and right heart function in humans.
dc.format.extent	340-344
dc.relation.ispartof	urn:issn:1064-1963
dc.title	Plasma VEGF levels and their relation to right ventricular function in pulmonary hypertension
dc.type	Journal Article
dc.date.updated	2019-09-13T11:07:27Z
dc.language.rfc3066	en
dc.rights.holder	NULL
dc.identifier.mtmt	2763972
dc.identifier.wos	000359846300011
dc.identifier.pubmed	25347703
dc.contributor.department	SE/AOK/K/Pulmonológiai Klinika
dc.contributor.institution	Semmelweis Egyetem