dc.contributor.author |
Bikov, András |
|
dc.contributor.author |
Lázár, Zsófia |
|
dc.contributor.author |
Gyulai, N |
|
dc.contributor.author |
Szentkereszty, Márton |
|
dc.contributor.author |
Losonczy, György |
|
dc.contributor.author |
Horváth, Ildikó |
|
dc.contributor.author |
Gálffy, Gabriella |
|
dc.date.accessioned |
2021-08-30T08:28:37Z |
|
dc.date.available |
2021-08-30T08:28:37Z |
|
dc.date.issued |
2015 |
|
dc.identifier |
84947491768 |
|
dc.identifier.citation |
journalVolume=193;journalIssueNumber=6;journalTitle=LUNG;pagerange=957-963;journalAbbreviatedTitle=LUNG; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/7820 |
|
dc.identifier.uri |
doi:10.1007/s00408-015-9778-7 |
|
dc.description.abstract |
PURPOSE: Lung cancer may be associated with airway acidification due to enhanced airway inflammation and oxidative stress. Exhaled breath condensate (EBC) pH is a non-invasive indicator of airway acidity; however, it is still unclear how EBC pH changes in lung cancer. The aim of the study was to investigate EBC pH in lung cancer together with clinical variables. METHODS: Thirty-five patients with lung cancer and 37 control subjects (21 patients with stable COPD and 16 non-COPD smokers) were enrolled. EBC was collected for pH, which was determined with the argon-purging method, compared among the groups and correlated with clinical variables of patients with lung cancer. RESULTS: No difference was found in EBC pH between patients with lung cancer and control subjects. However, endobronchial tumour localisation, squamous-cell carcinoma subtype and gastro-oesophageal reflux were associated with low EBC pH values. No relationship was observed between EBC pH and the presence of COPD, lung function variables or smoking history. CONCLUSIONS: Although, EBC pH is unchanged in lung cancer, lower EBC pH values are associated with distinct phenotypes. Our findings could facilitate further research on airway acidity in lung cancer. |
|
dc.format.extent |
957-963 |
|
dc.relation.ispartof |
urn:issn:0341-2040 |
|
dc.title |
Exhaled Breath Condensate pH in Lung Cancer, the Impact of Clinical Factors |
|
dc.type |
Journal Article |
|
dc.date.updated |
2019-09-23T11:27:51Z |
|
dc.language.rfc3066 |
en |
|
dc.rights.holder |
NULL |
|
dc.identifier.mtmt |
2928316 |
|
dc.identifier.wos |
000365284200012 |
|
dc.identifier.pubmed |
26260979 |
|
dc.contributor.department |
SE/AOK/K/Pulmonológiai Klinika |
|
dc.contributor.institution |
Semmelweis Egyetem |
|