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dc.contributor.author Akiyama, Hironori
dc.contributor.author Pesznyák, Csilla
dc.contributor.author Béla, Dalma
dc.contributor.author Ferenczi, Örs
dc.contributor.author Major, Tibor
dc.contributor.author Polgár, Csaba
dc.contributor.author Takácsi-Nagy, Zoltán
dc.date.accessioned 2020-03-25T12:09:30Z
dc.date.available 2020-03-25T12:09:30Z
dc.date.issued 2018
dc.identifier.citation journalVolume=52;journalIssueNumber=4;journalTitle=RADIOLOGY AND ONCOLOGY;pagerange=461-467;journalAbbreviatedTitle=RADIOL ONCOL;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/7871
dc.identifier.uri doi:10.2478/raon-2018-0042
dc.description.abstract Background The aim of the study was to present dosimetric comparison of image guided high-dose-rate brachytherapy (IGBT) with volumetric modulated arc therapy (VMAT) for head and neck cancer regarding conformity of dose distribution to planning target volume (PTV) and doses to organs at risk (OARs). Patients and methods Thirty-eight consecutive patients with T1-4 mobile tongue, floor of mouth and base of tongue cancer treated with IGBT were selected. For these patients additional VMAT treatment plans were also prepared using identical computed tomography data. OARs and PTV related parameters (e.g. V98, D0.1cm3, Dmean, etc.) were compared. Results Mean V98 of the PTV was 90.2% vs. 90.4% (p > 0.05) for IGBT and VMAT, respectively. Mean D0.1cm3 to the mandible was 77.0% vs. 85.4% (p < 0.05). Dmean to ipsilateral and contralateral parotid glands was 4.6% vs. 4.6% and 3.0% vs. 3.9% (p > 0.05). Dmean to ipsilateral and contralateral submandibular glands was 16.4% vs. 21.9% (p > 0.05) and 8.2% vs. 16.9% (p < 0.05), respectively. Conclusions Both techniques showed excellent target coverage. With IGBT dose to normal tissues was lower than with VMAT. The results prove the superiority of IGBT in the protection of OARs and the important role of this invasive method in the era of new external beam techniques.
dc.format.extent 461-467
dc.relation.ispartof urn:issn:1318-2099
dc.title Image guided high-dose-rate brachytherapy versus volumetric modulated arc therapy for head and neck cancer
dc.type Journal Article
dc.date.updated 2019-09-26T12:19:06Z
dc.language.rfc3066 en
dc.rights.holder NULL
dc.identifier.mtmt 30345155
dc.identifier.wos 000453416700013
dc.identifier.pubmed 30422804
dc.contributor.department SE/AOK/K/Onkológiai Tanszék
dc.contributor.institution Semmelweis Egyetem


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