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dc.contributor.author Rihmer Zoltán
dc.contributor.author Gonda Xénia
dc.contributor.author Torzsa Péter
dc.contributor.author Kalabay László
dc.contributor.author Akiskal HS
dc.contributor.author Eőry Ajándék
dc.date.accessioned 2015-01-07T15:39:32Z
dc.date.available 2015-01-07T15:39:32Z
dc.date.issued 2013
dc.identifier 84878488416
dc.identifier.citation pagination=350-354; journalVolume=149; journalIssueNumber=1-3; journalTitle=JOURNAL OF AFFECTIVE DISORDERS;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/921
dc.identifier.uri doi:10.1016/j.jad.2013.02.010
dc.description.abstract BACKGROUND: Untreated major affective disorders are strongly associated with suicidal behaviour; however, clinical, psychological and psycho-social risk factors also play a contributory role. Personal history and family history of suicide are also important predictors of suicidal behaviours, and are also a powerful marker of current major depressive episode in general practice patients. Affective temperaments, which can be considered the subaffective manifestations of major mood disorders also show a specific pattern of association with suicidal behaviour. In the present study our aim was to investigate the association between affective temperaments, personal history of suicide attempts and family history of completed suicide in primary practice patients. METHODS: Five hundred and nine patients from 6 primary care practices completed the TEMPS-A, and were assessed concerning self-reported history of personal or family suicide. RESULTS: We found that among those answering questions concerning suicide, 9.1% reported a family history of suicide in first and second degree relatives and 4.8% had at least one prior suicide attempt. Among those giving a positive answer to both questions, those who had a positive family history had significantly more frequent suicide attempts (15.4% vs. 4.0%). Patients with prior suicide attempts had a significantly higher score on the cyclothymic and depressive, and those with positive family history of suicide had on cyclothymic and anxious subscales. LIMITATIONS: In the present study, personal and family history of suicide was assessed retrospectively and in a self-report way. The cross-sectional nature of this study and the facts that no current psychiatric morbidity has been investigated and only the documented history of depressive and anxiety disorders have been detected limit the generalisability of this study. DISCUSSION: We found a significant relationship between depressive and cyclothymic affective temperament and personal history of suicide attempts, and between cyclothymic and anxious temperament and family history of completed suicide in first and second degree relatives. This is in line with previous findings showing a strong relationship between these affective temperaments and major mood episodes and that these temperaments are overrepresented among suicide attempters. Our findings also suggest that the presence of cyclothymic (and to lesser extent depressive) affective temperament in a patient with family history of completed suicide indicates a very high risk of suicidal behaviour.
dc.relation.ispartof urn:issn:0165-0327
dc.title Affective temperament, history of suicide attempt and family history of suicide in general practice patients
dc.type Journal Article
dc.date.updated 2015-01-06T13:24:13Z
dc.language.rfc3066 en
dc.identifier.mtmt 2240399
dc.identifier.wos 000320593000046
dc.identifier.pubmed 23477849
dc.contributor.department SE/ÁOK/K/Családorvosi Tanszék
dc.contributor.department SE/ÁOK/I/Farmakológiai és Farmakoterápiás Intézet
dc.contributor.department SE/KSZE/Kútvölgyi Klinikai Tömb Klinikai és Kutatási Mentálhigiénés Osztály
dc.contributor.department SE/ÁOK/K/Pszichiátriai és Pszichoterápiás Klinika
dc.contributor.institution Semmelweis Egyetem


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