PACAP38 and PACAP27 administered intracerebroventricularly have an opposite effect on LH secretion

dc.contributor.author	Kántor Orsolya
dc.contributor.author	Molnár Judith
dc.contributor.author	Arimura A
dc.contributor.author	Köves Katalin
dc.date.accessioned	2015-03-09T09:35:33Z
dc.date.available	2015-03-09T09:35:33Z
dc.date.issued	2000
dc.identifier.citation	pagination=817-820;journalVolume=21;journalIssueNumber=6;journalTitle=PEPTIDES;	hu
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/1417
dc.identifier.uri	doi:10.1016/S0196-9781(00)00214-X
dc.description.abstract	The effect of PACAP38 on the LH surge and ovulation was compared with that of PACAP27 and VIP in the same model. The peptides were administered intracerebroventricularly before the critical period of the proestrous stage. PACAP38 was able to inhibit ovulation and to prevent the preovulatory LH surge; however, PACAP27 did not inhibit the ovulation and VIP inhibited the ovulation in 2/11 animals. In those animals of the last two groups in which ovulation occurred, the preovulatory LH surge was higher than in control rats. It is speculated that the opposite effect of PACAP38 and PACAP27 on the preovulatory LH surge and ovulation is possibly mediated through different receptors.	hu
dc.relation.ispartof	urn:issn:0196-9781
dc.title	PACAP38 and PACAP27 administered intracerebroventricularly have an opposite effect on LH secretion	hu
dc.type	Journal Article	hu
dc.date.updated	2015-02-16T12:44:34Z
dc.language.rfc3066	en	hu
dc.identifier.mtmt	1871389
dc.identifier.wos	000089066400010
dc.identifier.pubmed	10959003
dc.contributor.department	SE/AOK/I/Humánmorfológiai és Fejlődésbiológiai Intézet
dc.contributor.institution	Semmelweis Egyetem