Browsing Folyóiratcikkek by Author "Csonka, Csaba"

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  • Schreckenberg R; Bencsik, Péter; Weber M; Abdallah Y; Csonka, Csaba; Gömöri, Kamilla; Kiss, Krisztina; Pálóczi, János; Pipis J; Sárközy, Márta; Ferdinandy, Péter; Schulz R; Schluter KD (2017)
    BACKGROUND: Ischemic preconditioning (IPC) and ischemic postconditioning (IPoC) are currently among the most efficient strategies protecting the heart against ischemia/reperfusion injury. However, the effect of IPC and ...
  • Sárközy, Márta; Fekete, Veronika; Szűcs, Gergő; Török, Szilvia; Szűcs, Csilla; Barkányi, Judit; Varga, Zoltán; Földesi, Imre; Csonka, Csaba; Kónya, Csaba; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    BACKGROUND: Although multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in diabetes mellitus, ...
  • Szűcs, Gergő; Murlasits, Zsolt; Török, Szilvia; Kocsis-Fodor, Gabriella; Pálóczi, János; Görbe, Anikó; Csont, Tamás Bálint; Csonka, Csaba; Ferdinandy, Péter (2013)
    Purpose: Farnesol is a key metabolite of the mevalonate pathway and known as an antioxidant. We examined whether farnesol treatment protects the ischemic heart. Methods: Male Wistar rats were treated orally with 0.2, 1, ...
  • Csonka, Csaba; Kupai, Krisztina; Bencsik, Péter; Görbe, Anikó; Pálóczi, János; Zvara, Ágnes; Puskás, László; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    It has been previously shown that hyperlipidemia interferes with cardioprotective mechanisms. Here we investigated the interaction of hyperlipidemia with cardioprotection induced by pharmacological activators of ATP-sensitive ...
  • Bencsik, Péter; Kupai, Krisztina; Görbe, Anikó; Kenyeres, Éva; Varga, Zoltán; Pálóczi, János; Gáspár, Renáta; Kovács László; Lutz Weber; Takács Ferenc; Hajdú, István; Fabó Gabriella; Cseh, Sándor; Barna, László; Csont, Tamás; Csonka, Csaba; Dormán, György; Ferdinandy, Péter (2018)
    The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and ...
  • Csont, Tamás Bálint; Sárközy, Márta; Szűcs, Gergő; Szűcs, Csilla; Barkányi, Judit; Bencsik, Péter; Gáspár, Renáta; Földesi, Imre; Csonka, Csaba; Kónya, Csaba; Ferdinandy, Péter (2013)
    BACKGROUND: Although complex multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in hyperlipidemia ...
  • Giricz, Zoltán; Koncsos, Gábor; Tomáš Rajtík; Varga, Zoltán; Baranyai, Tamás; Csonka, Csaba; Adrián Szobi; Adriana Adameová; Roberta A Gottlieb; Ferdinandy, Péter (2017)
    Background: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia ...
  • Kirca M; Kleinbongard P; Soetkamp D; Heger J; Csonka, Csaba; Ferdinandy, Péter; Schulz R (2015)
    Connexin 43 (Cx43), which is highly expressed in the heart and especially in cardiomyocytes, interferes with the expression of nitric oxide synthase (NOS) isoforms. Conversely, Cx43 gene expression is down-regulated by ...
  • Csonka, Csaba; Szűcs, Gergő; Varga-Orvos, Zoltán; Bencsik, Péter; Csont, Tamás Bálint; Zvara, Ágnes; Puskás, László; Ferdinandy, Péter (2014)
    To profile changes in gene expression in response to ischemic postconditioning, isolated rat hearts were subjected to 30 min of regional ischemia followed by 120 min of reperfusion with or without postconditioning. At the ...
  • Csonka, Csaba; Baranyai, Tamás; Tiszlavicz, László; Fébel, Hedvig; Szűcs, Gergő; Varga, Zoltán; Sárközy, Márta; Puskás, László; Antal, Otilia Tamara; Siska, Andrea; Földesi, Imre; Ferdinandy, Péter; Czakó, László; Csont, Tamás Bálint (2017)
  • Csonka, Csaba; Páli, Tibor; Bencsik, Péter; Görbe, Anikó; Ferdinandy, Péter; Csont, Tamás Bálint (2015)
  • Schreckenberg R; Weber P; Cabrera-Fuentes HA; Steinert I; Preissner KT; Bencsik, Péter; Sárközy, Márta; Csonka, Csaba; Ferdinandy, Péter; Schulz R; Schluter KD (2015)
    Cardiac ischaemia and reperfusion leads to irreversible injury and subsequent tissue remodelling. Initial reperfusion seems to shift arginine metabolism from nitric oxide (NO) to polyamine formation. This may limit functional ...
  • Sárközy, Márta; Zvara, Ágnes; Gyemant N; Fekete V; Kocsis-Fodor, Gabriella; Pipis, Judit; Szűcs, Gergő; Csonka, Csaba; Puskás, László; Ferdinandy, Péter; Csont, Tamás Bálint (2013)
    ABSTRACT: BACKGROUND: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac ...
  • Varga, Zoltán; Kupai, Krisztina; Szűcs, Gergő; Gáspár, Renáta; Pálóczi, János; Faragó, Nóra; Zvara, Ágnes; Puskás, László; Rázga, Zsolt; Tiszlavicz, László; Bencsik, Péter; Görbe, Anikó; Csonka, Csaba; Ferdinandy, Péter; Csont, Tamás Bálint (2013)
    Diet-induced hypercholesterolemia leads to oxidative/nitrative stress and subsequent myocardial dysfunction. However, the regulatory role of microRNAs in this phenomenon is unknown. We aimed to investigate, whether ...
  • Varga, Zoltán; Zvara, Ágnes; Faragó, Nóra; Kocsis-Fodor, Gabriella; Pipicz, Márton; Gáspár, Renáta; Bencsik, Péter; Görbe, Anikó; Csonka, Csaba; Puskás, László; Thum T; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    We aimed to characterize early changes in microRNA expression in acute cardioprotection by ischemic pre- and postconditioning in rat hearts. Hearts isolated from male Wistar rats were subjected to i) time-matched non-ischemic ...
  • Bencsik, Péter; Pálóczi, János; Kocsis-Fodor, Gabriella; Pipis, Judit; Belecz, István; Varga, Zoltán; Csonka, Csaba; Görbe, Anikó; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    Pharmacological inhibition of matrix metalloproteinase-2 (MMP-2) is a promising target for acute cardioprotection against ischemia/reperfusion injury. Therefore, here we investigated if the MMP inhibitor ilomastat administered ...
  • Kiss, Krisztina; Csonka, Csaba; Pálóczi, János; Pipis, Judit; Görbe, Anikó; Kocsis-Fodor, Gabriella; Murlasits Z; Sárközy, Márta; Szűcs, Gergő; Holmes CP; Pan Y; Bhandari A; Csont, Tamás Bálint; Shamloo M; Woodburn KW; Ferdinandy, Péter; Bencsik, Péter (2016)
    Erythropoietin (EPO) has been shown to protect the heart against acute myocardial infarction in pre-clinical studies, however, EPO failed to reduce infarct size in clinical trials and showed significant safety problems. ...
  • Schreckenberg, R; da Costa, Rebelo M; Deten, A; Weber, M; Rohrbach, S; Pipicz, Márton; Csonka, Csaba; Ferdinandy, Péter; Schulz, R; Schluter, KD (2015)
    AIMS: Research into right ventricular (RV) physiology and identification of pathomechanisms underlying RV failure have been neglected for many years because function of the RV is often considered to be less important for ...
  • Sárközy, Márta; Szűcs, Gergő; Pipicz, Márton; Zvara, Ágnes; Eder K; Fekete V; Szucs C; Barkanyi J; Csonka, Csaba; Puskás, László; Konya C; Ferdinandy, Péter; Csont, Tamás Bálint (2015)
    BACKGROUND: Diabetic patients have an increased risk of developing cardiovascular diseases, which are the leading cause of death in developed countries. Although multivitamin products are widely used as dietary supplements, ...
  • Kadomatsu K; Bencsik, Péter; Görbe, Anikó; Csonka, Csaba; Sakamoto K; Kishida S; Ferdinandy, Péter (2014)
    Ischemic heart disease, stroke and their pathological consequences are life-threatening diseases that account for about half of deaths in developed countries. Pathology of these diseases includes cell death due to ...

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