Show simple item record Tábi, Tamás Szökő, Éva Merey A, Tóth, Veronika Mátyus, Péter Gyires, Klára 2014-11-16T19:19:57Z 2014-11-16T19:19:57Z 2013
dc.identifier 84878741283
dc.identifier.citation pagination=963-967; journalVolume=120; journalIssueNumber=6; journalTitle=JOURNAL OF NEURAL TRANSMISSION;
dc.identifier.uri doi:10.1007/s00702-012-0961-1
dc.description.abstract SSAO/VAP-1 participates in the accumulation of leukocytes at the site of inflammation. A new SSAO inhibitor, SzV-1287 was demonstrated to inhibit both acute and chronic inflammation in rats more effectively than the known enzyme inhibitor, LJP-1207. Surprisingly, the SSAO activity was not increased, but decreased both in acute and chronic inflammation. Though experiments are in progress to clarify these findings, the enzyme might play a role in the very early phase of inflammation and be inactivated during leukocyte extravasation.
dc.relation.ispartof urn:issn:0300-9564
dc.title Study on SSAO enzyme activity and anti-inflammatory effect of SSAO inhibitors in animal model of inflammation.
dc.type Journal Article 2014-11-16T19:19:06Z
dc.language.rfc3066 en
dc.identifier.mtmt 2197197
dc.identifier.wos 000319433000016
dc.identifier.pubmed 23263543
dc.contributor.department SE/ÁOK/K/Bőr-, Nemikórtani és Bőronkológiai Klinika
dc.contributor.department SE/GYTK/Gyógyszerhatástani Intézet
dc.contributor.institution Semmelweis Egyetem

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