Folyóiratcikkek tallózása szerző szerint "Bognár, László"

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  • Cytogenetic Prognostication Within Medulloblastoma Subgroups 
    Shih, DJ; Northcott, PA; Remke, M; Korshunov, A; Ramaswamy, V; Kool, M; Luu, B; Yao, Y; Wang, X; Dubuc, AM; Garzia, L; Peacock, J; Mack, SC; Wu, X; Rolider, A; Morrissy, AS; Cavalli, FM; Jones, DT; Zitterbart, K; Faria, CC; Schuller, U; Kren, L; Kumabe, T; Tominaga, T; Shin, Ra Y; Garami, Miklós; Hauser, Péter; Chan, JA; Robinson, S; Bognár, László; Klekner, Álmos; Saad, AG; Liau, LM; Albrecht, S; Fontebasso, A; Cinalli, G; De Antonellis, P; Zollo, M; Cooper, MK; Thompson, RC; Bailey, S; Lindsey, JC; Di Rocco, C; Massimi, L; Michiels, EM; Scherer, SW; Phillips, JJ; Gupta, N; Fan, X; Muraszko, KM; Vibhakar, R; Eberhart, CG; Fouladi, M; Lach, B; Jung, S; Wechsler-Reya, RJ; Fevre-Montange, M; Jouvet, A; Jabado, N; Pollack, IF; Weiss, WA; Lee, JY; Cho, BK; Kim, SK; Wang, KC; Leonard, JR; Rubin, JB; de Torres, C; Lavarino, C; Mora, J; Cho, YJD; Tabori, U; Olson, JM; Gajjar, A; Packer, RJ; Rutkowski, S; Pomeroy, SL; French, PJ; Kloosterhof, NK; Kros, JM; Van, Meir EG; Clifford, SC; Bourdeaut, F; Delattre, O; Doz, FF; Hawkins, CE; Malkin, D; Grajkowska, WA; Perek-Polnik, M; Bouffet, E; Rutka, JT; Pfister, SM; Taylor, M (2014)
    PURPOSE: Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on clinical features: patient age, metastatic stage, extent ...
  • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma 
    Schwartzentruber, J; Korshunov, A; Liu, XY; Jones, DT; Pfaff, E; Jacob, K; Sturm, D; Fontebasso, AM; Quang, DA; Tonjes, M; Hovestadt, V; Albrecht, S; Kool, M; Nantel, A; Konermann, C; Lindroth, A; Jager, N; Rausch, T; Ryzhova, M; Korbel, JO; Hielscher, T; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Ebinger, M; Schuhmann, MU; Scheurlen, W; Pekrun, A;; Fruhwald, MC; Roggendorf, W; Kramm, C; Durken, M; Atkinson, J; Lepage, P; Montpetit, A; Zakrzewska, M; Zakrzewski, K; Liberski, PP; Dong, Z; Siegel, P; Kulozik, AE; Zapatka, M; Guha, A; Malkin, D; Felsberg, J; Reifenberger, G; von Deimling, A; Ichimura, K; Collins, VP; Witt, H; Milde, T; Witt, O; Zhang, C; Castelo-Branco, P; Lichter, P; Faury, D; Tabori, U; Plass, C; Majewski, J; Pfister, SM; Jabado, N (2012)
    Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression signatures indicate differences between adult and paediatric cases. To explore the genetic events ...
  • Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours 
    Jacob K; Albrecht S; Sollier C; Faury D; Sader E; Montpetit A; Serre D; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Montes JL; Atkinson J; Farmer JP; Bouffet E; Hawkins C; Tabori U; Jabado N (2009)
    BACKGROUND: Juvenile pilocytic astrocytomas (JPA), a subgroup of low-grade astrocytomas (LGA), are common, heterogeneous and poorly understood subset of brain tumours in children. Chromosomal 7q34 duplication leading to ...
  • Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR). 
    Mózes, Petra; Hauser, Péter; Hortobágyi, Tibor; Benyo G; Peták, István; Garami, Miklós; Cserháti, Adrienn; Bartyik K; Bognár, László; Nagy, Zoltán; Turányi, Eszter; Hideghéty, Katalin (2016)
    The embryonal tumor with abundant neuropil and true rosettes is a rare and highly malignant variant of embryonal brain tumors. It usually affects infants and young children under the age of 4 years and exhibits a very ...
  • Expression and Prognostic Examination of Heat Shock Proteins (HSP 27, HSP 70, and HSP 90) in Medulloblastoma 
    Hauser, Péter; Hanzély Z; Jakab, Zsuzsanna; Oláh L; Malét-Szabó, Erika; Jeney, András; Schuler, Dezső; Fekete, György; Bognár, László; Garami, Miklós (2006)
    Expression of heat shock proteins (HSPs) is of prognostic significance in several tumor types. HSP expression levels were determined in medulloblastomas and tested whether HSPs expression was associated with prognostic ...
  • Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR 
    Kleinman, CL; Gerges, N; Papillon-Cavanagh, S; Sin-Chan, P; Pramatarova, A; Quang, DA; Adoue, V; Busche, S; Caron, M; Djambazian, H; Bemmo, A; Fontebasso, AM; Spence, T; Schwartzentruber, J; Albrecht, S; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Montes, JL; Staffa, A; Montpetit, A; Berube, P; Zakrzewska, M; Zakrzewski, K; Liberski, PP; Dong, Z; Siegel, PM; Duchaine, T; Perotti, C; Fleming, A; Faury, D; Remke, M; Gallo, M; Dirks, P; Taylor, MD; Sladek, R; Pastinen, T; Chan, JA; Huang, A; Majewski, J; Jabado, N (2014)
    Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain tumors characterized by high-level amplification of the microRNA cluster C19MC. We performed integrated genetic and epigenetic analyses ...
  • Genome-wide Profiling Using Single-Nucleotide Polymorphism Arrays Identifies Novel Chromosomal Imbalances in Pediatric Glioblastomas 
    Qu HQ; Jacob K; Fatet S; Ge B; Barnett D; Delattre O; Faury D; Montpetit A; Solomon L; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Mio R; Farmer JP; Albrecht S; Polychronakos C; Hawkins C; Jabado N (2010)
  • High Incidence of Brain Tumors of Childhood in Hungary Between 1989 and 2001 
    Hauser, Péter; Jakab, Zsuzsanna; Láng, Orsolya; Kondás O; Török, Szabolcs János; Garami, Miklós; Bognár, László; Schuler, Dezső (2003)
  • Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma 
    Sturm, Dominik; Witt, Hendrik; Hovestadt, Volker; Khuong-Quang, Dong-Anh; Jones, David TW; Carolin, Konermann; Elke, Pfaff; Martje, Tönjes; Martin, Sill; Sebastian, Bender; Marcel, Kool; Marc, Zapatka; Natalia, Becker; Manuela, Zucknick; Thomas, Hielscher; Xiao-Yang, Liu; Adam, M Fontebasso; Marina, Ryzhova; Steffen, Albrecht; Karine, Jacob; Marietta, Wolter; Martin, Ebinger; Martin, U Schuhmann; Timothy, van Meter; Michael, C Frühwald; Holger, Hauch; Arnulf, Pekrun; Bernhard, Radlwimmer; Tim, Niehues; Gregor, von Komorowski; Matthias, Dürken; Andreas, E Kulozik; Jenny, Madden; Andrew, Donson; Nicholas, K Foreman; Rachid, Drissi; Maryam, Fouladi; Wolfram, Scheurlen; Andreas, von Deimling; Camelia, Monoranu; Wolfgang, Roggendorf; Christel, Herold-Mende; Andreas, Unterberg; Christof, M Kramm; Jörg, Felsberg; Christian, Hartmann; Benedikt, Wiestler; Wolfgang, Wick; Till, Milde; Olaf, Witt; Anders, M Lindroth; Jeremy, Schwartzentruber; Damien, Faury; Adam, Fleming; Magdalena, Zakrzewska; Pawel, P Liberski; Krzysztof, Zakrzewski; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Sorana, Morrissy; Florence, Cavalli; Michael, D Taylor; Peter, van Sluis; Jan, Koste; Rogier, Versteeg; Richard, Volckmann; Tom, Mikkelsen; Kenneth, Aldape; Guido, Reifenberger; V Peter, Collins; Jacek, Majewski; Andrey, Korshunov; Peter, Lichter; Christoph, Plass; Nada, Jabado; Stefan, M Pfister; (2012)
    Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable heterogeneity. We have recently identified recurrent H3F3A mutations affecting two critical amino acids (K27 and G34) of histone ...
  • Incidence and Survival of Central Nervous System Involvment in Childhood Malignancies: Hungarian Experience 
    Hauser, Péter; Jakab, Zsuzsanna; Láng, Orsolya; Kondás O; Müller, Judit; Schuler, Dezső; Bognár, László; Garami, Miklós (2005)
    Direct extension and hematogenous metastasis of primary non-CNS malignant tumors to the CNS are rare complications in children. The authors analyzed the incidence and outcome of these complications in Hungary. During ...
  • Molecular Profiling Identifies Prognostic Subgroups of Pediatric Glioblastoma and Shows Increased YB-1 Expression in Tumors. 
    Faury D; Nantel A; Dunn SE; Guiot MC; Haque T; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Liberski PP; Lopez-Aguilar E; Valera ET; Tone LG; Carret AS; Del Maestro RF; Gleave M; Montes JL; Pietsch T; Albrecht S; Jabado N (2007)
    PURPOSE: Pediatric glioblastoma (pGBM) is a rare, but devastating brain tumor. In contrast to GBM in adults (aGBM), little is known about the mechanisms underlying its development. Our aim is to gain insight into the ...
  • Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas 
    Fontebasso AM; Schwartzentruber J; Khuong-Quang D-A; Liu X-Y; Sturm D; Korshunov A; Jones DTW; Witt H; Kool M; Albrecht S; Fleming A; Hadjadj D; Busche S; Lepage P; Montpetit A; Staffa A; Gerges N; Zakrzewska M; Zakrzewski K; Liberski PP; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Zadeh G; Faury D; Pfister SM; Jabado N; Majewski J (2013)
    Recurrent mutations affecting the histone H3.3 residues Lys27 or indirectly Lys36 are frequent drivers of pediatric high-grade gliomas (over 30 % of HGGs). To identify additional driver mutations in HGGs, we investigated ...
  • MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma 
    Ryan S L; Schwalbe E C; Cole M; Lu Y; Lusher M E; Megahed H; O'Toole K; Nicholson S L; Bognár, László; Garami, Miklós; Hauser, Péter; Korshunov A; Pfister S M; Williamson D; Taylor R E; Ellison D W; Bailey S; Clifford S C (2012)
  • Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma 
    Al-Halabi H; Nantel A; Klekner, Álmos; Guiot MC; Albrecht S; Hauser, Péter; Garami, Miklós; Bognár, László; Kavan P; Gerges N; Shirinian M; Roberge D; Muanza T; Jabado N (2011)
  • Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. 
    Fontebasso AM; Papillon-Cavanagh S; Schwartzentruber J; Nikbakht H; Gerges N; Fiset PO; Bechet D; Faury D; De Jay N; Ramkissoon LA; Corcoran A; Jones DT; Sturm D; Johann P; Tomita T; Goldman S; Nagib M; Bendel A; Goumnerova L; Bowers DC; Leonard JR; Rubin JB; Alden T; Browd S; Geyer JR; Leary S; Jallo G; Cohen K; Gupta N; Prados MD; Carret AS; Ellezam B; Crevier L; Klekner, Álmos; Bognár, László; Hauser, Péter; Garami, Miklós; Myseros J; Dong Z; Siegel PM; Malkin H; Ligon AH; Albrecht S; Pfister SM; Ligon KL; Majewski J; Jabado N; Kieran MW (2014)
    Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor mutations encoding p.Lys27Met in histone H3 variants. In 40 treatment-naive mHGAs, 39 analyzed by ...
  • Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma 
    Zhukova N; Ramaswamy V; Remke M; Pfaff E; Shih DJ; Martin, DC; Castelo-Branco, P; Baskin, B; Ray, PN; Bouffet, E; von Bueren, AO; Jones, DT; Northcott, PA; Kool, M; Sturm, D; Pugh, TJ; Pomeroy, SL; Cho, YJ; Pietsch, T; Gessi, M; Rutkowski, S; Bognár, László; Klekner, Álmos; Cho, BK; Kim, SK; Wang, KC; Eberhart, CG; Fevre-Montange, M; Fouladi, M; French, PJ; Kros, M; Grajkowska, WA; Gupta, N; Weiss, WA; Hauser, Péter; Jabado, N; Jouvet, A; Jung, S; Kumabe, T; Lach, B; Leonard, JR; Rubin, JB; Liau, LM; Massimi, L; Pollack, IF; Shin, Ra Y; Van, Meir EG; Zitterbart, K; Schuller, U; Hill, RM; Lindsey, JC; Schwalbe, EC; Bailey, S; Ellison, DW; Hawkins, C; Malkin, D; Clifford, SC; Korshunov, A; Pfister, S; Taylor, MD; Tabori, U (2013)
    PURPOSE Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion of molecular subgroup profiles. PATIENTS AND METHODS We ...
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes 
    Northcott, PA; Shih, DJH; Peacock, J; Garzia, L; Sorana Morrissy, A; Zichner, T; Stütz, AM; Korshunov, A; Reimand, J; Schumacher, SE; Beroukhim, R; Ellison, DW; Marshall, CR; Lionel, AC; Mack, S; Dubuc, A; Yao, Y; Ramaswamy, V; Luu, B; Rolider, A; Cavalli, FMG; Wang, X; Remke, M; Wu, X; Chiu, RYB; Chu, A; Chuah, E; Corbett, RD; Hoad, GR; Jackman, SD; Li, Y; Lo, A; Mungall, KL; Ming, Nip K; Qian, JQ; Raymond, AGJ; Thiessen, N; Varhol, RJ; Birol, I; Moore, RA; Mungall, AJ; Holt, R; Kawauchi, D; Roussel, MF; Kool, M; Jones, DTW; Witt, H; Fernandez-L A; Kenney, AM; Wechsler-Reya, RJ; Dirks, P; Aviv, T; Grajkowska, WA; Perek-Polnik, M; Haberler, CC; Delattre, O; Reynaud, SS; Doz, FF; Pernet-Fattet, SS; Cho, B-K; Kim, S-K; Wang, K-C; Scheurlen, W; Eberhart, CG; Fèvre-Montange, M; Jouvet, A; Pollack, IF; Fan, X; Muraszko, KM; Yancey, Gillespie G; Di Rocco, C; Massimi, L; Michiels, EMC; Kloosterhof, NK; French, PJ; Kros, JM; Olson, JM; Ellenbogen, RG; Zitterbart, K; Kren, L; Thompson, RC; Cooper, MK; Lach, B; McLendon, RE; Bigner, DD; Fontebasso, A; Albrecht, S; Jabado, N; Lindsey, JC; Bailey, S; Gupta, N; Weiss, WA; Bognár, László; Klekner, Álmos; Van, Meter TE; Kumabe, T; Tominaga, T; Elbabaa, SK; Leonard, JR; Rubin, JB; Liau, LM; Van, Meir EG; Fouladi, M; Nakamura, H; Cinalli, G; Garami, Miklós; Hauser, Péter; Saad, AG; Iolascon, A; Jung, S; Carlotti, CG; Vibhakar, R; Shin, Ra Y; Robinson, S; Zollo, M; Faria, CC; Chan, JAD; Levy, ML; Sorensen, PHB; Meyerson, M; Pomeroy, SL; Cho, Y-J; Bader, GD; Tabori, U; Hawkins, CE; Bouffet, E; Scherer, SW; Rutka, JT; Malkin, D; Clifford, SC; Jones, SJM; Korbel, JO; Pfister, SM; Marra, MA; Taylor, MD (2012)
    Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits ...
  • TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. 
    Remke M,; Ramaswamy V,; Peacock J,; Shih DJ,; Koelsche C,; Bognár, László; Klekner, Álmos; Garami, Miklós; Hauser, Péter (2013)
    Telomerase reverse transcriptase (TERT) promoter mutations were recently shown to drive telomerase activity in various cancer types, including medulloblastoma. However, the clinical and biological implications of TERT ...